Archive for November, 2006

MDMA’s verbal memory – a LTE

November 29, 2006

Researchers evidencing illicit club drug harms seemingly ignore Ecstasy’s [MDMA] popularity, or the contextual dangers stemming directly from its illegal status. [NZH 29Nov] Nor do they make a comparison with known harms from early use of that other culturally acceptable anesthetic drug, Alcohol. The ‘verbal memory’ of drunken adults would discourage any thinking teen if the double standards in drug education didn’t get in the way.

 

Gt.Britain’s rational and refreshingly balanced response announced recently by UK Professor Nutt, is to downgrade MDMA and LSD. Like Cannabis, ‘on evidence’ the harms have been largely overstated. The UK Science and Technology Select Committee further advised the principles underpinning ‘ABC’ drug classification was seriously deficient saying it was about political expediency and criminal status rather than relative harms. NZ could well take on board these points as it considers what to do about medicinal and recreational cannabis. Drug policy must be formulated around informed consent. That is the adult thing to do. Young folk, according to WellTrust have unfettered access to all manner of drugs and in a very dangerous context, a point that prohibition has a lot to answer for.  As adults we have an ethical if not moral imperative to fix this, and soon.

 

Blair Anderson

Director, Educators for Sensible Drug Policy

http://www.efsdp.org

 

(200 words)

On Medpot and Crime, California Dreamin / ;-)

November 28, 2006

“Relief from the burden of criminality through medical protection enhances a salutary self-perception.”

(also see “Marijuana – the Anti-Drug” – physicians are finding that patients using cannabis are reducing use of conventional prescription medications or even discarding them completely.)

Demographics:

  • male patients, 72; female, 28%.
  • Women are more likely than men to use cannabis for psychotherapeutic purposes (32% to 18%).
  • Men are more likely to use for harm reduction (4% to 1%).

/Blair

Fred Gardner: Dr. Mikuriya’s Observations 10 Years of Legalized Medical Marijuana in California

Posted by Gary Storck / Saturday, November 4, 2006

It’s hard to believe that 10 years have passed since California voters passed Prop 215. While there has been much progress in that time, there continues to be too much pain and suffering, caused by the U.S. government’s failure to listen to its people and the science. While some areas of California have good access to medical cannabis, like the San Francisco Bay Area, the fight continues in other areas. In some locales, local authorities are teaming up with the DEA to close dispensaries. Even in places like San Francisco, a NIMBY backlash is threatening to push dispensaries out of neighborhoods where patients can easily access their medicine.

The good news is hundreds of thousands of patients ARE getting their medicine, and much has been learned from these patients. The passage of Prop 215 has helped inspire 10 other states to pass medical marijuana laws. And in those areas where local officials have been supportive, patients now have access to a wide selection of different strains, hash, kif, edibles, capsules, tinctures, salves and more. Vaporizers are cheaper, more efficient and more commonplace. Activist groups like CA NORML, Americans for Safe Access and DPA are fighting against the backlash and having success sticking up for patients. While the US war on the sick and dying shows no signs of abating, hopefully the next ten will be smoother. There is even a little hope for action at the federal level should Democrats retake Congress. I’ll be exploring the election results and their impact Tuesday night on this blog.

Below, Fred Gardner details Dr. Tod Mikuriya’s observations ten years after. Dr. Mikuriya was last in Madison in 2005 when he spoke at the 35th Great Midwest Marijuana Harvest Festival.

Dr. Mikuriya’s Observations 10 Years of Legalized Medical Marijuana in California

By FRED GARDNER

Tod Mikuriya, MD (Berkeley), was the first California doctor to monitor patients’ use of cannabis systematically. In the early 1990s his interviews with members of the San Francisco Cannabis Buyers Club documented Dennis Peron’s observation that people were self-medicating for an extremely wide range of problems.

The broad range of applications confirmed what Mikuriya had learned from his study of the pre-prohibition medical literature on cannabis, and so when Prop 215 was being drafted, he urged that it apply not only to people with a list of named conditions, but to those treating ” … any other illness for which marijuana provides relief.”

No sooner had Prop 215 passed than top California law enforcement agents colluded with Clinton Administration officials and Prohibitionist strategists from the private sector to plan its disimplementation. On Dec. 30, 1996, Drug Czar Barry McCaffrey, Attorney General Janet Reno, Health & Human Services Secretary Donna Shalala, and the director of the National Institute of Drug Abuse, Alan Leshner, held a press conference to threaten California doctors with loss of their licenses, i.e., their livelihoods, if they approved marijuana use by their patients. McCaffrey stood alongside a large chart headed “Dr. Tod Mikuriya’s, (215 Medical Advisor) Medical Uses of Marijuana.” Twenty-six conditions were listed in two columns. (“Migranes” was misspelled.) “This isn’t medicine, this is a Cheech and Chong show,” he said. Reno said prosecutors would focus on doctors who were “egregious” in approving marijuana use by patients.

Dr. Mikuriya watched the press conference on CNN at his home in the Berkeley Hills. “As doctors become more fearful,” he says. “I’ll obviously get more and more patients who are using cannabis or are considering it. Will that make it seem that there’s something ‘egregious’ about my practice? You bet it will!”

From the Attorney General’s office in Sacramento a memo went out from Senior Deputy AG John Gordnier to district attorneys in all 58 counties asking them to forward any cases involving Mikuriya. In due course, on the basis of complaints from sheriffs, cops, and DAs, Mikuriya was investigated by the medical board and found to have committed “extreme departures from standard practice.” He was placed on probation and ordered to pay $75,000 for his own prosecution.

Over the years the number of cannabis specialists among California doctors has risen slowly but steadily. In 2000 Mikuriya organized a group, now known as the Society of Cannabis Clinicians, to share data for research purposes. More than 20 doctors have become involved with the SCC. Collectively they have approved cannabis use by an estimated 350,000 patients. This summer, with the 10th anniversary of Prop 215’s passage approaching, I surveyed the SCC doctors get their basic findings. Here are Dr. Mikuriya’s responses to the survey he inspired.

Approvals issued to date: 8,684.
Previously self-medicating: >99%
Category of use: Analgesic/immunomodulator 41%
Antispasmodic/anticonvulsant 29%
Antidepresssant/Anxiolytic 27%
Harm reduction substitute: 4%

Results reported are dependent on the conditions and symptoms being treated. The primary benefit is control without toxicity for chronic pain and a wide array of chronic conditions. Control represents freedom from fear and oppression. Control -or lack thereof- is a major element in self-esteem.

With exertion of control, with freedom from fear of incapacity, quality of life is improved. The ability to abort an incapacitating attack of migraine, asthma, anxiety, or depression empowers.

Relief from the burden of criminality through medical protection enhances a salutary self-perception.

Alteration in the perception of and reaction to pain and muscle spasticity is a unique property of cannabis therapy.

Patient reports are diverse yet contain common elements. 100% report that cannabis is safe and effective. Return for follow-up and renewal of recommendation and approval confirms safety and efficacy.

Cannabis seems to work by promoting homeostasis in various systems of the body. Its salient effects are multiple and concurrent. They include- o Restoration of normal functioning of the gastrointestinal tract with normalization of peristalsis and restoration of appetite. o Normalizing circadian rhythm, which relieves insomnia. Sleep is therapeutic in itself and synergistically helps with pain control. o Easement of pain, depression, and anxiety. Cannabis as an anxiolytic and antidepressant modulates emotional reactivity and is especially useful in treating post-traumatic stress disorders.

Patients treated for ADHD: 92
Patients using cannabis as a substitute for alcohol: 683.
The slow poisoning by alcohol with its sickening effects on the body, psyche, and family can be relieved by cannabis.

Medications no longer needed? Opioids, sedatives, NSAIDS (non-steroidal anti-inflammatories), and SSRI anti-depressants are commonly used in smaller amounts or discontinued. These are all drugs with serious adverse effects. Opioids and sedatives produce depression, demotivation, and diminished mobility. Weight gain and diminished functionality are common effects. Cognitive and emotional impairment and depression are comorbid conditions. Opioids adversely effect vegetative functioning with constipation, dyspepsia, and gastric irritation. Pruritus is also an issue for some. Circadian rhythms are disrupted with sleep disorders and chronic sedation caused by these agents. Dependence and withdrawal symptoms are more serious than with sedatives.

Opioids are undoubtedly the analgesic of choice in treating acute pain. For chronic pain, however, I recommend the protocol proposed by a doctor named Fronmueller2 to the Ohio Medical Society in 1859: primary use of cannabis, resorting to opiates for episodic worsening of the condition. Efficacy is maximized, tolerance and adverse effects are minimized. (Neither cannabis nor human physiology has changed since 1859.)

NSAIDs can be particularly insidious for those who do not immediately react with gastric irritation and discontinue the drug. Chronic irritation with bleeding may produce serious morbidity. Most often, the dyspepsia produced is suppressed with antacids or other medications. Many patients tolerate acute intermittent use but not chronic use. SSRIs, if tolerated, coexist without adverse interaction with cannabis. Some SSRI users say cannabis is synergistic in that it treats side effects of jitteriness or gastrointestinal problems.

Many patients report pressure exerted by the Veterans Administration, HMOs such as Kaiser Permanente, and workers’ compensation program contractors to remain on pharmaceutical regimens. A significant number describe their prescribed drugs as ineffectual and having undesirable effects. “Mainstream” doctors frequently respond to reports of adverse effects by prescribing additional drugs. Instead of negating the problem, they often complicate it. Prevailing practice standards encourage polypharmacy -the use of multiple drugs, usually five or more.

Out of the ordinary conditions? While all pain reflects localized immunologic activity secondary to trauma or injury, the following atraumatic autoimmune disorders comprise a group of interest: Crohn’s disease Atrophie blanche, Melorheostosis, Porphyria, Thallasemia, Sickle cell anemia, Amyloidosis Mastocytosis, Lupus, Scleroderma, Eosinophilia myalgia syndrome. These are all clearly of autoimmune etiology, difficult to treat. Specific metabolic errors such as amyloidosis and certain anemias warrant further study and may elucidate the underlying mechanisms of the illnesses and the therapeutic effects of cannabis. Multiple sclerosis with its range of severity varies in therapeutic response to cannabis.

Demographics: male patients, 72; female, 28%. Women are more likely than men to use cannabis for psychotherapeutic purposes (32% to 18%). Men are more likely to use for harm reduction (4% to 1%). A roughly bell-shaped curve describes the age of my patients. 0-18 years, 1%; 19-30, 19%; 31-45, 36%; 45-60, 37%; older than 61, 7%.

Additional Observations:

Proactive structuralism works. Meaning: people can create something and by doing so, set a precedent.

Medical cannabis users are typically treating chronic illnesses – not rapidly debilitating acute illnesses.

The cash economy works better than the bureaucratic alternative. Word of mouth builds a movement.

The private sector is handling marijuana distribution because the government has defaulted.

Cannabis was once on the market and regulated, then it was removed from the market and nearly forgotten.

Not all that we’ve learned in the past 10 years is new.

Once upon a time the California Compassionate Use Act of 1996 became the law of the state. We had the mistaken belief that civil servants, sworn to uphold the law, would set about implementing the new section of the Health & Safety Code. Hardly… Twenty California doctors have been investigated by the Medical Board for approving cannabis use by their patients. Limited immunity from prosecution for physicians was either proclaimed invalid or, more commonly, evaded by the Board and the Attorney General. They dissimulate, pretending that it is not the physician’s approval of marijuana at issue, but his or her standard of practice. They then hold cannabis consultants to a standard that most HMO doctors violate constantly.

The fix is in. The state criminal justice entities share information and operate in concert with the DEA. There has been a total end run around the injunctive protection of the Conant ruling. [In Conant, a federal court enjoined the government from threatening doctors who discuss cannabis as a treatment option with patients.] General media indifference enables this RICO under color of authority and the continuing defiance of the will of Californians who spoke ten years ago.

This is counterbalanced by the rewards of helping patients with serious chronic aliments who have adverse experience utilizing so-called main stream medicines.

Fred Gardner can be reached at fred@plebesite.com

http://www.madisonnorml.org/blog/archives/000112.php


Blair Anderson
ph (643) 389 4065 cell 027 265 7219

BMJ on C&C to MFE

November 27, 2006

Katie Andrews-Cookson
Advisor, Climate Change
Ministry for the Environment.
Wellington

Hi Katie…

Increasingly broadening debate amongst health professionals in the august journal BMJ on Beyond Kyoto principals.. (as well as an objective critique on why they have been quiet, none more so than here). Also this informative editorial confirms the Assoc of British Architects are similarly aligned to C&C.

http://www.bmj.com/cgi/content/full/333/7576/983

Blair Anderson
http://mildgreens.com

Life-chemistry of cannabis

November 26, 2006
Long time internet collegue Dr. Robert [Bob] Melamede is assistant professor (and Chair of Biology) at UCCS. He presented at the 2006 NORML [USA] conference. Find out how the physics of life works and why cannabinoids play such a crucial role [mp3] with one of the most respected researchers and best presenters on the subjects of the actual life-chemistry of cannabis .
 
Blair Anderson
ph (643) 389 4065   cell 027 265 7219
 

Beyond Sativex

November 25, 2006

While Sativex (a metered dosage whole cannabis preparation) proves the lie, a new study published in the November 2006 Harm Reduction Journal suggests the health outcomes issue is wider than just what one can be prescribed (and thus morally approved).

Here is some selected notes from the Canadian research.

Valid clinical studies of herbal cannabis require a product which is acceptable to patients in order to maximize adherence to study protocols. (Sounds awfully like informed consent to me./Blair) The study shows that medical cannabis users can appreciate differences in herbal product. A more acceptable cannabis product may increase recruitment and retention in clinical studies of medical cannabis.

To our knowledge, this is the first ever evaluation of medical cannabis products for physical and smoking characteristics by authorized patients. We have shown that subjects may appreciate differences between cannabis preparations on the basis of physical characteristics of the herbal material, specifically general appearance and colour. We did not show differences in individual smoking characteristics, but overall impressions confirmed that subjects favoured higher THC content, higher humidity and larger grind size.

The detected differences between products could have arisen by chance, or may have been influenced by other factors such as the use of different modes of administration (pipes and joints). Further study should limit the modes of administration to reduce confounding by these factors. (Au contraire… the study should be enhanced to provide research insight into modes of use…/Blair)

Like Wow Man… some godamn honesty makes for a refreshing change…
Lets see if the NZ Green Party understand the significance and support ‘home grow’ and to seek the repeal of the bong bill for its inconsistencies and breaches of good faith and human rights.

Consider the wider implications of cannabis use as replacement therapy (hell its supposed to work for methadone, why not cannabis? ). THere is a legacy of exonerative testimony that cannabis replaces alchol. Thats a major head start in harm reduction/minimisation.

Marijuana, the Anti-Drug

The extent to which medical cannabis users discontinue or reduce their use of pharmaceutical and over-the-counter drugs is a recurring theme in a recent survey of pro-cannabis (PC) California doctors. The drug-reduction phenomenon has obvious scientific implications. Medicating with cannabis enables people to lay off stimulants as well as sedatives -suggesting that the herb’s active ingredients restore homeostasis to various bodily systems. (Lab studies confirm that cannabinoids normalize the tempo of many other neurotransmission systems.) The political implications are equally obvious. Legalizing herbal cannabis would devastate the pharmaceutical manufacturers and allied corporations in the chemicals, oil, “food,” and banking sectors. Put simply, the synthetic drug makers stand to lose half their sales if and when the American people get legal access to cannabis.

In the 10 years since Proposition 215 made it legal for California doctors to approve cannabis use by patients, the PC docs did not adopt a common intake questionnaire, and, with one exception, did not collect systematic data on which pharmaceutical drugs their patients had chosen to stop taking. However, the consistency with which the doctors describe this phenomenon has a force as impressive as any slickly presented “hard” data.

Blair Anderson
http://mildgreens.com

Give heroin to addicts, says Police Chief

November 24, 2006

Separately, the [UK] government’s drugs adviser, David Nutt, said that ecstasy and LSD, which are believed to be used by half a million young people every week, should be downgraded from class A.

One would have to ask, what then is our Expert Advisoy Committee on Drugs doing?

This interesting milestone in the public discourse on drug policy also mentions former Metropolitan police detective chief superintendent Eddie Ellison who many readers will recall said much the same thing as our Mr Nutt on TV3’s Mikey Havoc’s interview. (see LEAP NZ tour April 2004)

Blair Anderson
http://mildgreens.com

Green MP takes offence over Maori drug use suggestions

November 22, 2006

(it appears neither commentators understand white priviledge. /Blair)

Green MP Meteria Turei has taken offence over generalisations about Maori after an addiction expert said the group was more at risk of becoming drug addicts than others.

NZPA reported this week National Addiction Centre director Professor Doug Sellman’s study results which found Maori were twice as likely to have lifetime substance use disorders than other ethnic groups.

In an interview on National Radio yesterday he speculated cultural reasons could have an effect. Differences he pointed to included singing and ability at sports which Ms Turei said was “deeply offensive”.

“Addiction is an enormously complex issue for everyone who suffers from it. Social and economic factors as well as the impact of colonialism and racism must be seriously considered in analysing this data.”

Ms Turei said a 2002 Christchurch School of Medicine report on arrests and convictions for cannabis related offences showed Maori had a higher rate of convictions for those offences because they were stopped and searched more.

“This morning’s comments were simplistic and unfair. For such research to have beneficial impacts for Maori the analysis of causality needs to be far more sophisticated,” Ms Turei said.

On Tuesday Prof Sellman had said the reasons for the result were not fully understood but underscored the need for effective services to be available.

Prof Sellman said that while complete recovery from severe addiction was relatively rare, recovery of a worthwhile life was achievable.

“But to achieve this, people must be retained in treatment for longish periods of time to consolidate behaviour change and skills acquisition,” he said.

[NZPA]

Blair Anderson
http://mildgreens.com

NORML Advisory Board Member Robert Altman Dies

November 21, 2006

Noted Director, NORML Advisory Board Member Robert Altman Dies
November 21, 2006 – Los Angeles, CA, USA

[Robert Altman joined NORML’s Advisory Board in 2002, six years after he had major heart transplant surgery. Robert was a lifetime user of cannabis, and outsdpoken advocate for reform. If this escaped the notice of media, it must allso be noted that Robert’s artistic (and business) success puts paid to the notion that cannabis is a dumb drug. The truth will out. /Blair]


[image courtesy of Thighs Wide Shut

Los Angeles, CA: Filmmaker Robert Altman, director of dozens of films and television dramas, passed away today. He was 81 years old. Altman’s received critical accolades for much of his work, most notably the film “MASH,” as well 1975’s “Nashville” and the 1971 western “McCabe and Mrs. Miller.”

He was nominated as best director for “MASH,” “Nashville,” “The Player” (1992), “Short Cuts” (1993) and “Gosford Park” (2001). Earlier this year, Altman received a lifetime achievement award from the Academy of Motion Picture Arts and Sciences.

Condolences to his Whanau and Friends from the MildGreens.
Blair Anderson
http://mildgreens.com

Youth Targetting… (or so goes the War)

November 19, 2006

A MAJOR new drive to catch people on illegal drugs is being launched in Winchester tonight and is targeting young people visiting the city’s pubs.

In a groundbreaking operation, police will be testing people on their way into four city pubs and stopping and searching anyone who gives a positive result.

It is one of the first times that the machine, called Ion-Track, has been used in the UK to test people on their way into venues. It can detect everything from cannabis to crack.

see: Basingstoke Gazette

Blair Anderson
http://mildgreens.com

LEAP: Milton Friedman, Obit

November 19, 2006

Milton Friedman, the Nobel Prize-winning economist who advocated an unfettered free market and had the ear of three U.S. presidents, died Thursday at age 94.
A member of LEAP, Milton Friedman was a pioneer of the anti-drug war movement who tirelessly advocated for an end to the “War on Drugs” throughout his life. As recently as 2005, Friedman led a list of more than 500 economists who publicly endorsed Harvard University **economist’s report on the costs of marijuana prohibition and the potential revenue gains from the U.S. government instead legalizing it and taxing its sale. “I’ve long been in favor of legalizing all drugs,” he said, but not because of the standard libertarian arguments for unrestricted personal freedom. “Look at the factual consequences: The harm done and the corruption created by these laws…the costs are one of the lesser evils.”
Can any policy, however high-minded, be moral if it leads to widespread corruption, imprisons so many, has so racist an effect, destroys our inner cities, wreaks havoc on misguided and vulnerable individuals, and brings death and destruction to foreign countries?
** Prof Jeffery Miron, friend of Clifford Wallace Thortnon Jr. who also toured New Zealand prior to the LEAP tour (Apr 2004)
Blair Anderson
http://mildgreens.com